Pesquisa | BVS Aleitamento Materno

1.

Structure-based design of non-hypertrophic apelin receptor modulator.

Wang, Wei-Wei; Ji, Su-Yu; Zhang, Wenjia; Zhang, Junxia; Cai, Chenxi; Hu, Rubi; Zang, Shao-Kun; Miao, Luwei; Xu, Haomang; Chen, Li-Nan; Yang, Zongkuai; Guo, Jia; Qin, Jiao; Shen, Dan-Dan; Liang, Ping; Zhang, Yan; Zhang, Yan.

Cell; 187(6): 1460-1475.e20, 2024 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-38428423

2.

Cytoneme signaling provides essential contributions to mammalian tissue patterning.

Hall, Eric T; Dillard, Miriam E; Cleverdon, Elizabeth R; Zhang, Yan; Daly, Christina A; Ansari, Shariq S; Wakefield, Randall; Stewart, Daniel P; Pruett-Miller, Shondra M; Lavado, Alfonso; Carisey, Alex F; Johnson, Amanda; Wang, Yong-Dong; Selner, Emma; Tanes, Michael; Ryu, Young Sang; Robinson, Camenzind G; Steinberg, Jeffrey; Ogden, Stacey K.

Cell; 187(2): 276-293.e23, 2024 01 18.

Artigo em Inglês | MEDLINE | ID: mdl-38171360

3.

Snapshot of the cannabinoid receptor 1-arrestin complex unravels the biased signaling mechanism.

Liao, Yu-Ying; Zhang, Huibing; Shen, Qingya; Cai, Chenxi; Ding, Yu; Shen, Dan-Dan; Guo, Jia; Qin, Jiao; Dong, Yingjun; Zhang, Yan; Li, Xiao-Ming.

Cell; 186(26): 5784-5797.e17, 2023 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-38101408

4.

Mapping transcriptomic vector fields of single cells.

Qiu, Xiaojie; Zhang, Yan; Martin-Rufino, Jorge D; Weng, Chen; Hosseinzadeh, Shayan; Yang, Dian; Pogson, Angela N; Hein, Marco Y; Hoi Joseph Min, Kyung; Wang, Li; Grody, Emanuelle I; Shurtleff, Matthew J; Yuan, Ruoshi; Xu, Song; Ma, Yian; Replogle, Joseph M; Lander, Eric S; Darmanis, Spyros; Bahar, Ivet; Sankaran, Vijay G; Xing, Jianhua; Weissman, Jonathan S.

Cell; 185(4): 690-711.e45, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-35108499

5.

Glycyl Radical Enzymes and Sulfonate Metabolism in the Microbiome.

Wei, Yifeng; Zhang, Yan.

Annu Rev Biochem; 90: 817-846, 2021 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-33823652

6.

Structural insights into the human D1 and D2 dopamine receptor signaling complexes.

Zhuang, Youwen; Xu, Peiyu; Mao, Chunyou; Wang, Lei; Krumm, Brian; Zhou, X Edward; Huang, Sijie; Liu, Heng; Cheng, Xi; Huang, Xi-Ping; Shen, Dan-Dan; Xu, Tinghai; Liu, Yong-Feng; Wang, Yue; Guo, Jia; Jiang, Yi; Jiang, Hualiang; Melcher, Karsten; Roth, Bryan L; Zhang, Yan; Zhang, Cheng; Xu, H Eric.

Cell; 184(4): 931-942.e18, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33571431

7.

Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences.

Kumar, Sushant; Warrell, Jonathan; Li, Shantao; McGillivray, Patrick D; Meyerson, William; Salichos, Leonidas; Harmanci, Arif; Martinez-Fundichely, Alexander; Chan, Calvin W Y; Nielsen, Morten Muhlig; Lochovsky, Lucas; Zhang, Yan; Li, Xiaotong; Lou, Shaoke; Pedersen, Jakob Skou; Herrmann, Carl; Getz, Gad; Khurana, Ekta; Gerstein, Mark B.

Cell; 180(5): 915-927.e16, 2020 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-32084333

8.

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.

Wang, Jun; Xu, Yanhui; Chen, Zhanghua; Liang, Jiankun; Lin, Zefeng; Liang, Huiying; Xu, Yiping; Wu, Qi; Guo, Xuanjie; Nie, Junli; Lu, Bingtai; Huang, Bing; Xian, Huifang; Wang, Xiaohui; Wu, Qiang; Zeng, Jixiao; Chai, Chengwei; Zhang, Meixue; Lin, Yuzhen; Zhang, Li; Zhao, Shanmeizi; Tong, Yanlu; Zeng, Liang; Gu, Xiaoqiong; Chen, Zhuang-Gui; Yi, Shuhong; Zhang, Tong; Delfouneso, David; Zhang, Yan; Nutt, Stephen L; Lew, Andrew M; Lu, Liwei; Bai, Fan; Xia, Huimin; Wen, Zhe; Zhang, Yuxia.

Cell; 183(7): 1867-1883.e26, 2020 12 23.

Artigo em Inglês | MEDLINE | ID: mdl-33248023

9.

Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways.

Huang, Bing; Chen, Zhanghua; Geng, Lanlan; Wang, Jun; Liang, Huiying; Cao, Yujie; Chen, Huan; Huang, Wanming; Su, Meiling; Wang, Hanqing; Xu, Yanhui; Liu, Yukun; Lu, Bingtai; Xian, Huifang; Li, Huiwen; Li, Huilin; Ren, Lu; Xie, Jing; Ye, Liping; Wang, Hongli; Zhao, Junhong; Chen, Peiyu; Zhang, Li; Zhao, Shanmeizi; Zhang, Ting; Xu, Banglao; Che, Di; Si, Wenyue; Gu, Xiaoqiong; Zeng, Liang; Wang, Yong; Li, Dingyou; Zhan, Yifan; Delfouneso, David; Lew, Andrew M; Cui, Jun; Tang, Wai Ho; Zhang, Yan; Gong, Sitang; Bai, Fan; Yang, Min; Zhang, Yuxia.

Cell; 179(5): 1160-1176.e24, 2019 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-31730855

10.

Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex.

Qu, Qianhui; Takahashi, Yoh-Hei; Yang, Yidai; Hu, Hongli; Zhang, Yan; Brunzelle, Joseph S; Couture, Jean-Francois; Shilatifard, Ali; Skiniotis, Georgios.

Cell; 174(5): 1117-1126.e12, 2018 08 23.

Artigo em Inglês | MEDLINE | ID: mdl-30100186

11.

Author Correction: STEEP mediates STING ER exit and activation of signaling.

Zhang, Bao-Cun; Nandakumar, Ramya; Reinert, Line S; Huang, Jinrong; Laustsen, Anders; Gao, Zong-Liang; Sun, Cheng-Long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong-Gang; Stenmark, Harald; Doucet, Christine M; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J; Enghild, Jan J; Bak, Rasmus O; Thomsen, Martin K; Paludan, Søren R.

Nat Immunol; 21(11): 1468-1469, 2020 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-32929276

12.

STEEP mediates STING ER exit and activation of signaling.

Zhang, Bao-Cun; Nandakumar, Ramya; Reinert, Line S; Huang, Jinrong; Laustsen, Anders; Gao, Zong-Liang; Sun, Cheng-Long; Jensen, Søren Beck; Troldborg, Anne; Assil, Sonia; Berthelsen, Martin F; Scavenius, Carsten; Zhang, Yan; Windross, Samuel J; Olagnier, David; Prabakaran, Thaneas; Bodda, Chiranjeevi; Narita, Ryo; Cai, Yujia; Zhang, Cong-Gang; Stenmark, Harald; Doucet, Christine M; Noda, Takeshi; Guo, Zheng; Goldbach-Mansky, Raphaela; Hartmann, Rune; Chen, Zhijian J; Enghild, Jan J; Bak, Rasmus O; Thomsen, Martin K; Paludan, Søren R.

Nat Immunol; 21(8): 868-879, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32690950

13.

The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome.

Zhu, Fangrui; Ma, Juan; Li, Weitao; Liu, Qiannv; Qin, Xiwen; Qian, Yan; Wang, Chunlei; Zhang, Yan; Li, Yi; Jiang, Dong; Wang, Shuo; Xia, Pengyan.

Immunity; 56(4): 753-767.e8, 2023 04 11.

Artigo em Inglês | MEDLINE | ID: mdl-37001519

14.

Multivalent Small-Molecule Pan-RAS Inhibitors.

Welsch, Matthew E; Kaplan, Anna; Chambers, Jennifer M; Stokes, Michael E; Bos, Pieter H; Zask, Arie; Zhang, Yan; Sanchez-Martin, Marta; Badgley, Michael A; Huang, Christine S; Tran, Timothy H; Akkiraju, Hemanth; Brown, Lewis M; Nandakumar, Renu; Cremers, Serge; Yang, Wan Seok; Tong, Liang; Olive, Kenneth P; Ferrando, Adolfo; Stockwell, Brent R.

Cell; 168(5): 878-889.e29, 2017 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-28235199

15.

Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.

Hu, Chunyi; Myers, Mason T; Zhou, Xufei; Hou, Zhonggang; Lozen, Macy L; Nam, Ki Hyun; Zhang, Yan; Ke, Ailong.

Mol Cell; 84(3): 463-475.e5, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-38242128

16.

Conformational transitions and activation of the adhesion receptor CD97.

Mao, Chunyou; Zhao, Ru-Jia; Dong, Ying-Jun; Gao, Mingxin; Chen, Li-Nan; Zhang, Chao; Xiao, Peng; Guo, Jia; Qin, Jiao; Shen, Dan-Dan; Ji, Su-Yu; Zang, Shao-Kun; Zhang, Huibing; Wang, Wei-Wei; Shen, Qingya; Sun, Jin-Peng; Zhang, Yan.

Mol Cell; 84(3): 570-583.e7, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-38215752

17.

Naturally Occurring Off-Switches for CRISPR-Cas9.

Pawluk, April; Amrani, Nadia; Zhang, Yan; Garcia, Bianca; Hidalgo-Reyes, Yurima; Lee, Jooyoung; Edraki, Alireza; Shah, Megha; Sontheimer, Erik J; Maxwell, Karen L; Davidson, Alan R.

Cell; 167(7): 1829-1838.e9, 2016 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-27984730

18.

IL-1ß-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance.

Han, Yi; Zhang, Yan-Yu; Pan, Yi-Qian; Zheng, Xiao-Jun; Liao, Kun; Mo, Hai-Yu; Sheng, Hui; Wu, Qi-Nian; Liu, Ze-Xian; Zeng, Zhao-Lei; Yang, Wei; Yuan, Shu-Qiang; Huang, Peng; Ju, Huai-Qiang; Xu, Rui-Hua.

Mol Cell; 83(11): 1887-1902.e8, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-37244254

19.

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells.

Guo, Fan; Yan, Liying; Guo, Hongshan; Li, Lin; Hu, Boqiang; Zhao, Yangyu; Yong, Jun; Hu, Yuqiong; Wang, Xiaoye; Wei, Yuan; Wang, Wei; Li, Rong; Yan, Jie; Zhi, Xu; Zhang, Yan; Jin, Hongyan; Zhang, Wenxin; Hou, Yu; Zhu, Ping; Li, Jingyun; Zhang, Ling; Liu, Sirui; Ren, Yixin; Zhu, Xiaohui; Wen, Lu; Gao, Yi Qin; Tang, Fuchou; Qiao, Jie.

Cell; 161(6): 1437-52, 2015 Jun 04.

Artigo em Inglês | MEDLINE | ID: mdl-26046443

20.

Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems.

Tan, Renke; Krueger, Ryan K; Gramelspacher, Max J; Zhou, Xufei; Xiao, Yibei; Ke, Ailong; Hou, Zhonggang; Zhang, Yan.

Mol Cell; 82(4): 852-867.e5, 2022 02 17.

Artigo em Inglês | MEDLINE | ID: mdl-35051351

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